A recent study found that an oxidation-antioxidant imbalance in the blood is an early indicator of Alzheimer’s. The study showed that oxidative markers, known to be involved in Alzheimer’s disease, are increased up to 5 years before the onset of the disease in people with the APOE4 gene.

The oxidative markers, discovered in the study, can be detected by a blood test. These markers are found in plasma extracellular vesicles, the particles released by any cells that play a role in intercellular communication.

The researchers believe that by identifying oxidative markers in the blood of people at risk 5 years before the onset of the disease, it is possible to slow the onset of the disease and limit the risks before it is too late. In this case they propose 2 ways: either modulate the antioxidant systems, such as apolipoproteins J and D (transport of lipids and cholesterol in the blood) or increase antioxidant intake through diet.

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