A recent study found causal genetic links to the changed blood levels of 3 metabolites that increase the risk of migraine. To refresh your memory, metabolites are substances made during metabolism when the body breaks down food, drugs, or chemicals.

The 3 identified metabolites are:

(1) DHA (docosahexaenoic acid) that is able to reduce inflammation and therefore protect against migraine. The lower levels of DHA are linked inflammation, heart and brain diseases, but also to migraines.

(2) LPE (20:4) (lysophosphatidylethanolamine), a chemical that blocks the production of an anti-inflammatory molecule anandamide. The higher levels of this chemical don’t allow our body to appropriately fight inflammation. According to researchers, if LPE(20:4) could be controlled, this might prevent migraine.

(3) Currently uncharacterised metabolite X–11315. Its lower levels seem to increase the risk of migraine.

The researchers explained that the changes in blood levels of the mentioned metabolites might be due to diet, lifestyle, and genetics. Therefore it is possible to return these levels to optimal by a careful diet planning and supplementation. What exactly you need to eat and in what amounts to prevent migraine is the topic for further investigation.

Curious? HERE is the source

Tatsiana Haponava, PhD

a certified nutrition coach, educator and researcher with a PhD degree

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