Our brain has an immune system with its microglia cells that aim to protect neurons from any damage. In healthy people microglia cells facilitate the neurons’ function. In case of Alzheimer’s, they defend neurons by surrounding the accumulation of highly toxic substances, known as ameloid plaques, preventing their spread in the brain and decreasing damage. Microglia cells can do their job if they have enough supply of nutrients and oxygen. A recent study discovered that low oxygen levels reduce the microglia’s defensive capacity against the disease, increasing the chance of developing Alzheimer’s.

The researchers believe that the low oxygen levels lead to the increased expression of the HIF1 molecule that regulates the response of the cells to low oxygen. Increased HIF1 levels compromise the mitochondrial activity of microglia’s and limit their protective capacity against Alzheimer’s.

In case you wonder, what can cause low oxygen levels on the first place? Most probably other on-going illnesses such as heart and blood vessel diseases (in other words, cardiovascular diseases).

Knowing that, you need to pay extra attention to your heart health to prevent possible lack of oxygen in your brain.

Curious? HERE is the source