Actually no. According to a large analysis of existing studies on this topic, evidence that opioids (f.e. hydrocodone, oxycodone, oxymorphone, morphine, codeine, fentanyl) provide pain relief for migraine headaches, is low or insufficient. The researchers analyzed 15 systematic reviews and 115 randomized clinical trials of 28.803 patients and came to conclusion that many patients respond differently to the migraine treatment. However, there were also several well established and newer therapies, that are able to help deal with migraine pain better than opiods.

For instance, the study found that triptans or NSAIDS (nonsteroidal anti-inflammatory drugs such as aspirin, diclofenac, ibuprofen and ketorolac), or a combination of these two provided the largest evidence-base for pain relief at 2 hours, as well 1 day after symptoms began. 2 newer treatments recently approved by FDA (the Food and Drug Administration), ubrogepant and rimegepant, had moderate to high strength of evidence and mild side effects. Lasmiditan, another new therapy, also had a high strength of evidence, but also was linked to a significant risk of side effects.

Among devices, external vagus nerve (located at the side of the neck) stimulation and remote electrical neuromodulation (located over the arm) each had moderate strength of evidence. External trigeminal nerve (located over the brows) stimulation and transcranial magnetic stimulation (located over the back of the head) showed slightly less strength of evidence.

Curious? HERE is the source